This is what I've tried so far from a google search: I've tested other programs such as Word, Excel, Pictures, text files - they all work fine in preview. No updates were installed at this time that I recall (although checking my update history I see KB4483234 installed the day before I shut down) but now I've turned my PC on, no errors or alerts on opening and my preview won't work. It was working fine before the Xmas holidays and I shut my PC down. I'm having an issue on my Windows 10 Pro PC (version 1803, build 17134.472) with Adobe Acrobat Reader DC (version 2019.010.20064) and not being able to use panel preview in Windows Explorer.